Quinine Tolerance in Pregnancy
نویسنده
چکیده
A European lady, aged about 30 years, had bilious vomiting on 23rd October, 1936, at about midnight. In the morning of 24th October her temperature was 99.4?F. She was sick off and on, and could not retain anything. Previous history.?She went out for a picnic on 23rd October, 1936, in the morning in a forest near a river. AVhen she came back in the evening she did not feel well. At about midnight she started bilious vomiting with undigested food and she also felt feverish. She had suffered from malaria once or twice previously. She came to the Dooars about a year ago.
منابع مشابه
Clinical Pharmacology of the Antimalarial Quinine in Children
Quinine is the best studied drug for treating severe malaria in very young children. Quinine may be administered in pregnancy and, at therapeutic doses, malformations have not been reported. Some strains of quinine from Southeast Asia and South America have become resistant. Quinine is the treatment of choice for the drug-resistant severe Plasmodium falciparum. The antimalarial mechanism of qui...
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متن کاملQuinine Tolerance in Pregnancy
Sir,?The above article in the December 1937 issue interested me very much because it raises some other points. The patient was given nine 10-grain quinine injections intramuscularly,. thrice daily and on consecutive days. In the London School of Tropical Medicine and Hygiene they condemn most emphatically intramuscular injections of quinine. They say quinine causes tissue necrosis, much of the ...
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The fact that quinine is used to overcome uterine inertia in weak women, and as an ecbolic is always prescribed during labour, if there is no obstruction, is mainly responsible for the general impression that its use should be avoided during pregnancy as far as possible. Clinical experience, however, warrants no such fear about the administration of quinine during pregnancy. Hare, in his Practi...
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